Department of Internal Medicine
University of Utah
Salt Lake City, Utah
VA Med. Center, SLC
GRECC building 2 Rm 2D20
500 Foothill Drive
Salt Lake City, UT-84148
I am interested in exploring the cellular molecular mechanisms in microvascular endothelial cell in cerebral cavernous malfunction disease and evaluating potential drug to treat the disease. I am also interested in the interaction between immune cell and vascular endothelial cell in aging and metabolic abnormalities.
TTT Phuong, SN Redmon, O Yarishkin, JM Winter, DY Li, D Krizaj. Calcium influx through TRPV4 channels modulates the adherens contacts between retinal microvascular endothelial cells. The Journal of Physiology (2017)
Ryskamp AD*, Frye AM*, Phuong TTT*, Yarishkin O, Jo AO, Xu Y, Lakk M, Iuso A, Redmon SN, Ambati B, Hageman G, Prestwich GD, Torrejon KY and Križaj D. TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye. Scientific Reports (2016). *Equal contribution.
Phuong TTT, Yarishkin O, Križaj D. Subcellular propagation of calcium waves in Müller glia does not require autocrine/paracrine purinergic signaling. Channels (2016)
Kim TH, Kwon CH, Lee C, An J, Phuong TTT, Park SH, Lima MD, Baughman RH, Kang TM, Kim SJ. Bio-inspired hybrid carbon nanotube muscles. Scientific Reports (2016); 6: 26687.
Jo AO, Lakk M, Fry AM, Phuong TTT, Redmon SR, Roberts R, Berkowitz BA, Yarishkin O, Križaj D. Differential volume regulation and calcium signaling in two ciliary body cell types is subserved by TRPV4 channels. Proceedings of the National Academy of Sciences of the USA (2016); 113(14): 3885-90.
Molnar T, Yarishkin O, Iuso A, Barabas P, Jones B, Mark RE, Phuong TTT, Križaj D. Store-operated calcium entry in Müller glia is controlled by synergistic activation of TRPC and Oral channels. Journal of Neuroscience (2016); 36(11): 3184-98.
Jo AO, Ryskamp DA, Phuong TTT, Verkman AS, Yarishkin O, MacAulay N, Križaj D. TRPV4 and AQP4 channels synergistically regulate cell volume and calcium homeostasis in retinal Müller glia. Journal of Neuroscience 2015; 35(39): 13525-37.
Phuong TTT, Kang TM. Stromal interaction molecule 2 regulates C2C12 myoblast differentiation. Integrative Medicine Research 2015; 4(4): 242-8.
Lee BC, Kim HJ, Park SH, Phuong TTT, Kang TM, Park CS. Development of cell-based assay system that utilizes a hyperactive channel mutant for high-throughput screening of BK(Ca) channel modulators. Journal of Biotechnology 2013; 167(1): 41-6.
Phuong TTT, Yun Y-H, Kim SJ, Kang TM. Positive feedback control between STIM1 and NFATc3 is required for C2C12 myoblast differentiation. Biochemical and Biophysical Research Communications 2013; 430(2):722-8.