2013 Publications

Morgan RG, Ives SJ, Walker AE, Cawthon RM, Andtbacka RH, Noyes RD, Lesniewski LA,  Richarchson RS, Donato AJ. Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping.  J. OF HYPERTENSION (In press)

Donato AJ, Lesniewski LA, Stuart D, Walker AE, Henson GD, Sorensen L, Li DY, Kohan DE. Smooth Muscle Specific Disruption of the Endothelin-A Receptor in Mice Reduces Arterial Pressure, Vascular Reactivity and Affects Vascular Development. LIFE SCIENCES (In press)

Walker AE, Henson GD, Reihl KD, Nielson EI, Morgan RG, Lesniewski LA, Donato AJ. Beneficial effects of lifelong caloric restriction on endothelial function are greater in conduit arteries compared to cerebral resistance arteries. AGE:1-11. 2013

Lesniewski LA, Zigler ML, Durrant JR, Nowlan MJ, Folian BJ, Donato AJ, Seals DR. Aging compounds western diet-associated large artery endothelial dysfunction in mice: Prevention by voluntary aerobic exercise. EXP. GERONTOLOGY 48:1218-1225. 2013

Davis RT 3rd, Stabley JN, Dominguez JM 2nd, Ramsey MW, McCullough DJ, Lesniewski LA, Delp MD, Behnke BJ. Differential effects of aging and exercise on intra-abdominal adipose arteriolar function and blood flow regulation. J. APPL. PHYSIOL.114: 808-815. 2013

Morgan RG, Ives SJ, Lesniewski LA, Cawthon RM, Andtbacka RH, Noyes RD, Richarchson RS, Donato AJ.Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries AM. J. PHYSIOL. HEART and CIRC. H251-H258. 2013

Donato AJ, Walker AE, Magerko KA, Bramwell RC, Black AD, Henson GD, Lawson BR, Lesniewski LA, Seals DR. Life-Long Caloric Restriction Reduces Oxidative Stress and Preserves Nitric Oxide Bioavailability and Function in Arteries of Old Mice. AGING CELL 12:772-783. 2013

Barrett-O’Keefe Z, Ives SJ, Trinity JD, Morgan RG, Rossman MJ, Donato AJ, Runnels S, Morgan DE, Gmelch BS, Bledsoe AD, Richardson RS, Wray DW. Taming the “Sleeping Giant”: The Role of Endothelin-1 in the Regulation of Skeletal Muscle Blood Flow and Arterial Blood Pressure during Exercise.  AM. J. PHYSIOL. HEART and CIRC. 304: H162-H169. 2013